MRI with intrathecal gadolinium to detect a CSF leak: a prospective open-label cohort study.
Identifieur interne : 001288 ( Main/Exploration ); précédent : 001287; suivant : 001289MRI with intrathecal gadolinium to detect a CSF leak: a prospective open-label cohort study.
Auteurs : RBID : pubmed:20562454English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Cerebrospinal Fluid Rhinorrhea (diagnosis), Cohort Studies, Contrast Media (administration & dosage), Contrast Media (adverse effects), Female, Gadolinium (administration & dosage), Gadolinium (adverse effects), Gadolinium (diagnostic use), Humans, Injections, Spinal (adverse effects), Intracranial Hypotension (complications), Intracranial Hypotension (diagnosis), Magnetic Resonance Imaging (adverse effects), Magnetic Resonance Imaging (methods), Male, Meningitis, Bacterial (complications), Meningitis, Bacterial (diagnosis), Middle Aged.
- MESH :
- chemical , administration & dosage : Contrast Media, Gadolinium.
- chemical , adverse effects : Contrast Media, Gadolinium.
- adverse effects : Injections, Spinal, Magnetic Resonance Imaging.
- complications : Intracranial Hypotension, Meningitis, Bacterial.
- diagnosis : Cerebrospinal Fluid Rhinorrhea, Intracranial Hypotension, Meningitis, Bacterial.
- chemical , diagnostic use : Gadolinium.
- methods : Magnetic Resonance Imaging.
- Adolescent, Adult, Aged, Cohort Studies, Female, Humans, Male, Middle Aged.
Abstract
The techniques currently used to detect a cerebrospinal fluid (CSF) leak are an indium radionucleotide scan and a CT scan with intrathecal iodinated contrast agent. They have a low spatial and temporal resolution and are unpleasant for the patient. This open-label prospective observational cohort study was designed to investigate the feasibility, success ratio, complications and therapeutic consequences of MRI with gadolinium administered by lumbar puncture to detect a CSF leak.
DOI: 10.1136/jnnp.2009.180752
PubMed: 20562454
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">MRI with intrathecal gadolinium to detect a CSF leak: a prospective open-label cohort study.</title><author><name sortKey="Vanopdenbosch, Ludo J" uniqKey="Vanopdenbosch L">Ludo J Vanopdenbosch</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology AZ Sint Jan Brugge Oostende AV, Ruddershove 10, Brugge 8000, Belgium. ludo.vanopdenbosch@azbrugge.be</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Neurology AZ Sint Jan Brugge Oostende AV, Ruddershove 10, Brugge 8000</wicri:regionArea></affiliation></author><author><name sortKey="Dedeken, Peter" uniqKey="Dedeken P">Peter Dedeken</name></author><author><name sortKey="Casselman, Jan W" uniqKey="Casselman J">Jan W Casselman</name></author><author><name sortKey="Vlaminck, Stephan A P A" uniqKey="Vlaminck S">Stephan A P A Vlaminck</name></author></titleStmt><publicationStmt><date when="2011">2011</date><idno type="doi">10.1136/jnnp.2009.180752</idno><idno type="RBID">pubmed:20562454</idno><idno type="pmid">20562454</idno><idno type="wicri:Area/Main/Corpus">001888</idno><idno type="wicri:Area/Main/Curation">001888</idno><idno type="wicri:Area/Main/Exploration">001288</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Cerebrospinal Fluid Rhinorrhea (diagnosis)</term><term>Cohort Studies</term><term>Contrast Media (administration & dosage)</term><term>Contrast Media (adverse effects)</term><term>Female</term><term>Gadolinium (administration & dosage)</term><term>Gadolinium (adverse effects)</term><term>Gadolinium (diagnostic use)</term><term>Humans</term><term>Injections, Spinal (adverse effects)</term><term>Intracranial Hypotension (complications)</term><term>Intracranial Hypotension (diagnosis)</term><term>Magnetic Resonance Imaging (adverse effects)</term><term>Magnetic Resonance Imaging (methods)</term><term>Male</term><term>Meningitis, Bacterial (complications)</term><term>Meningitis, Bacterial (diagnosis)</term><term>Middle Aged</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Contrast Media</term><term>Gadolinium</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Contrast Media</term><term>Gadolinium</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Injections, Spinal</term><term>Magnetic Resonance Imaging</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Intracranial Hypotension</term><term>Meningitis, Bacterial</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cerebrospinal Fluid Rhinorrhea</term><term>Intracranial Hypotension</term><term>Meningitis, Bacterial</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Gadolinium</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Magnetic Resonance Imaging</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Cohort Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The techniques currently used to detect a cerebrospinal fluid (CSF) leak are an indium radionucleotide scan and a CT scan with intrathecal iodinated contrast agent. They have a low spatial and temporal resolution and are unpleasant for the patient. This open-label prospective observational cohort study was designed to investigate the feasibility, success ratio, complications and therapeutic consequences of MRI with gadolinium administered by lumbar puncture to detect a CSF leak.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">20562454</PMID><DateCreated><Year>2011</Year><Month>03</Month><Day>16</Day></DateCreated><DateCompleted><Year>2011</Year><Month>05</Month><Day>11</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1468-330X</ISSN><JournalIssue CitedMedium="Internet"><Volume>82</Volume><Issue>4</Issue><PubDate><Year>2011</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Journal of neurology, neurosurgery, and psychiatry</Title><ISOAbbreviation>J. Neurol. Neurosurg. Psychiatr.</ISOAbbreviation></Journal><ArticleTitle>MRI with intrathecal gadolinium to detect a CSF leak: a prospective open-label cohort study.</ArticleTitle><Pagination><MedlinePgn>456-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1136/jnnp.2009.180752</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The techniques currently used to detect a cerebrospinal fluid (CSF) leak are an indium radionucleotide scan and a CT scan with intrathecal iodinated contrast agent. They have a low spatial and temporal resolution and are unpleasant for the patient. This open-label prospective observational cohort study was designed to investigate the feasibility, success ratio, complications and therapeutic consequences of MRI with gadolinium administered by lumbar puncture to detect a CSF leak.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Patients were selected with either confirmed liquorrhoea, recurrent bacterial meningitis, or symptoms, and MRI findings of spontaneous intracranial hypotension. High-resolution T1 weighted MRI with fat suppression of the spinal column at 1 h and of the brain at 6 and 24 h postinjection of 0.5 ml of gadolinium were performed.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">27 patients were included. The clinically suspected CSF leak was found in six of eight patients with liquorrhoea, three of five patients with recurrent bacterial meningitis and nine of 14 patients with spontaneous intracranial hypotension. The procedure was easy to perform and generally well tolerated. One patient developed streptococcal meningitis in the hours following the procedure but recovered completely with antibiotic treatment. 17 of 18 patients in whom a dural defect was found underwent surgery. All patients became symptom-free after closure of the dural leak.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Spinal cord and brain MRI after intrathecal gadolinium injection is an easy-to-perform and accurate technique for detection of a dural defect with excellent anatomical detail.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vanopdenbosch</LastName><ForeName>Ludo J</ForeName><Initials>LJ</Initials><Affiliation>Department of Neurology AZ Sint Jan Brugge Oostende AV, Ruddershove 10, Brugge 8000, Belgium. ludo.vanopdenbosch@azbrugge.be</Affiliation></Author><Author ValidYN="Y"><LastName>Dedeken</LastName><ForeName>Peter</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Casselman</LastName><ForeName>Jan W</ForeName><Initials>JW</Initials></Author><Author ValidYN="Y"><LastName>Vlaminck</LastName><ForeName>Stephan A P A</ForeName><Initials>SA</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Evaluation Studies</PublicationType><PublicationType>Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2010</Year><Month>06</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Neurol Neurosurg Psychiatry</MedlineTA><NlmUniqueID>2985191R</NlmUniqueID><ISSNLinking>0022-3050</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Contrast Media</NameOfSubstance></Chemical><Chemical><RegistryNumber>AU0V1LM3JT</RegistryNumber><NameOfSubstance>Gadolinium</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease">Cerebrospinal fluid leak</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Cerebrospinal Fluid Rhinorrhea</DescriptorName><QualifierName MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Contrast Media</DescriptorName><QualifierName MajorTopicYN="Y">administration & dosage</QualifierName><QualifierName MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Gadolinium</DescriptorName><QualifierName MajorTopicYN="N">administration & dosage</QualifierName><QualifierName MajorTopicYN="N">adverse effects</QualifierName><QualifierName MajorTopicYN="Y">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Injections, Spinal</DescriptorName><QualifierName MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Intracranial Hypotension</DescriptorName><QualifierName MajorTopicYN="N">complications</QualifierName><QualifierName MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Magnetic Resonance Imaging</DescriptorName><QualifierName MajorTopicYN="N">adverse effects</QualifierName><QualifierName MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Meningitis, Bacterial</DescriptorName><QualifierName MajorTopicYN="N">complications</QualifierName><QualifierName MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="aheadofprint"><Year>2010</Year><Month>6</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>6</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>6</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2011</Year><Month>5</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pii">jnnp.2009.180752</ArticleId><ArticleId IdType="doi">10.1136/jnnp.2009.180752</ArticleId><ArticleId IdType="pubmed">20562454</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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